Sofosbuvir and Daclatasvir -Uses, Side Effects & Warnings

What is daclatasvir?

• Daclatasvir is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body.
• Daclatasvir is used in combination with other medications to treat chronic hepatitis C in adults.
• Daclatasvir treats specific genotypes of hepatitis C, and only in certain people. Use only the medications prescribed for you. Do not share your medicine with other people.
• Daclatasvir must be given in combination with other antiviral medications and should not be used alone. Daclatasvir is usually given with sofosbuvir, with or without ribavirin.
• Daclatasvir is sometimes used in people who also have HIV. Daclatasvir is not a treatment for HIV or AIDS.

Uses of Sofosbuvir and Daclatasvir

Daclatasvir

• A total of 194 drugs are known to interact with daclatasvir.
• Daclatasvir is in the drug class NS5A inhibitors.
• Daclatasvir is used to treat Hepatitis C.

Sofosbuvir

• A total of 30 drugs are known to interact with sofosbuvir.
• Sofosbuvir is a member of the drug class miscellaneous antivirals.
• Sofosbuvir is used to treat Hepatitis C.

Sofosbuvir and Daclatasvir Dosage

Daclatasvir Tablet If you notice within 20 hours of the time you usually take Daclactasvir, you must take the tablet as soon as possible. Then take the next dose at your usual time.
If you notice more than 20 hours after the time you usually take Daclactasvir, wait and take the next dose at your usual time. Do not take a double dose (two doses close together).
Sofosbuvir If you notice within 18 hours of the time you usually take Sofosbuvir, you must take the tablet as soon as possible. Then take the next dose at your usual time.
If you notice 18 hours or more after the time you usually take Sofosbuvir, wait and take the next dose at your usual time. Do not take a double dose (two doses close together).

Warning  Sofosbuvir and Daclatasvir tablet

The concomitant use of Daclactasvir, Sofosbuvir and other drugs may result in known or potentially significant drug interactions, some of which may lead to loss of therapeutic effect of Daclactasvir, Sofosbuvir and possible development of resistance, dosage adjustments of concomitant medications or Daclactasvir, Sofosbuvir,possible clinically significant adverse reactions from greater exposures of concomitant drugs or Daclactasvir, Sofosbuvir.
Drugs contraindicated with Daclactasvir, Sofosbuvir due to loss of efficacy and possible development of resistance for steps to prevent or manage other possible and known significant drug interactions. Consider the potential for drug interactions before and during Daclactasvir, Sofosbuvir therapy, review concomitant medications during Daclactasvir, Sofosbuvir therapy, and monitor for the adverse reactions associated with the concomitant drugs.
Serious Symptomatic Bradycardia When Coadministered With Sofosbuvir And Amiodarone
Postmarketing cases of symptomatic bradycardia and cases requiring pacemaker intervention have been reported when amiodarone is coadministered with sofosbuvir in combination with another HCV direct-acting antiviral, including Daclactasvir, Sofosbuvir.

Side Effects of Sofosbuvir and Daclatasvir

Daclatasvir, like all other medicines, has some side effects.
Most of these are minor and will settle within a few days or weeks

• Feeling sick (nausea)
• Diarrhoea
• Tiredness
• Headaches.
• Sofosbuvir Tab, like all other medicines, has some side effects.

Storage of Sofosbuvir and Daclatasvir

There are no special storage instructions for Daclatasvir Tab, Sofosbuvir; however they should be kept in a safe place, away from children.